Clomid (clomiphene citrate) >>
Clomid (clomiphene citrate) is a prescription medicine used to induce regular ovulation in women willing to become pregnant but unable to do so due to a number of reasons. Clomid works by stimulating the production of follicle-stimulating hormone in the pituitary gland and helps to establish an ovulation. Clomid actually increases the amount of three hormones that participate in the ovulation process including luteinizing hormone, follicle-stimulating hormone and gonadotropin-releasing hormone as a result of which the body is tricked to believe the levels of estrogen are low and ovaries mature more follicles. Another way this drug can be used is to increase the number of follicles for the IVF treatment procedure. Once this goal is reached the dosage does not need to be increased any more and usually three months of such infertility therapy is enough for most patients to get pregnant. Clomid is a great options for couples unable to conceive dues to certain reasons but not able to afford IVF treatment because of the high cost.
Clomid treatment is usually prescribed after the cause of infertility is established and the partner’s semen is analyzed. The treatment is then carefully monitored by a specially trained endocrinologist. Some tests may also be required – for instance, ultrasound monitoring of follicular development. Clomid is usually not taken for longer than 6 cycles. If that didn’t help the next option is in vitro fertilization. It has been estimated that about 25% of all infertility cases are caused by problems with ovulation. Clomid is a very easy to use medicine that has very few side effects and is comparatively cheap. At the same time it provides for up to 80% of efficiency, which means 8 out of 10 women will get pregnant after the course of treatment. Between 70 and 90 percent of women start ovulating within the first three cycles of the treatment, while 40% of women get pregnant within the same time period. Clomid is not expected to work if the woman has blocked fallopian tubes.
Every doctor may have a slightly different routine according to which you will be supposed to take this medicine. In most cases the patients are prescribed the 50 mg dosage of Clomid and are supposed to take it for 5 days, starting with day 3 of the cycle or day 5 of the cycle. It’s therefore very important that you listen carefully to all the instructions your doctor gives. If you happened to miss a dose – call your health care provider and ask what you are supposed to do for your treatment to be beneficial.
Certain side effects Clomid may cause include breast tenderness, hot flashes, nausea, mood swings and some other ones that will stop once you stop taking Clomid. However, considering the fact you only need to use Clomid for 5 days your health care provider may recommend sticking to the original routine and completing the treatment in spite of the side effects mentioned above. When taking Clomid you have a higher risk of giving birth to twins – the probability is actually 10%, while triplets and other multiples constitute another 1%. Sometimes Clomid can decrease the quality of your cervical mucus, making it more difficult for the sperm to meet the egg. It has been also reported to make the lining of the uterus thinner and less hospitable for the fertilized egg to be implanted.
One of the risks associated with taking Clomid is the potential of developing OHSS (ovarian hyperstimulation syndrome) with complications such as twisting of the ovaries, kidney or liver problems and accumulation of fluid in stomach and lungs. If you did not respond to the most commonly prescribed dose of 50 mg your health care provider may prescribe a higher dose of 100 mg. In some cases even the highest – 250 mg dosage may be attempted but this may not work for all patients as some women happen to be Clomid resistant. There may be certain reasons why you are Clomid resistant – including being overweight (BMI over 25) and having been diagnosed with hyperprolactinemia. In case of being overweight the recommendation your health care provider may give is to lose some weight – losing 10% of your weight may actually do the trick.
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